Umbilical cord blood transplant. High doses of chemotherapy and radiation can cause severe mucositis (inflammation of the mouth and GI tract). The number of transplants being done for an increasing number of diseases, as well as ongoing medical developments, have greatly improved the outcome for bone marrow transplant in children and adults. At Another Johns Hopkins Member Hospital: Acute Lymphocytic Leukemia (ALL): Symptoms. WebMD does not provide medical advice, diagnosis or treatment. It will stay there until after your treatment. In some cases, the stem cells come from the placenta and umbilical cord of a newborn baby. You’ll probably be awake for this, but it shouldn’t hurt. A haploid-identical match is when the donor is a parent and the genetic match is at least half identical to the recipient. The group of specialists involved in the care of patients going through transplant is often referred to as the transplant team. All individuals work together to give the best chance for a successful transplant. Bone marrow transplant (BMT) is a special therapy for patients with certain cancers or other diseases. Your doctors and nurses will keep a close watch on you as you recover. The nurse coordinator will provide patient education, and coordinates the diagnostic testing and follow-up care. It doesn’t hurt, and you won’t need to stay in the hospital. A bone marrow transplant is a procedure to replace damaged or diseased bone marrow, a spongy material inside your bones where your body makes and stores blood cells, with healthy marrow. Low platelets can cause dangerous bleeding in the lungs, gastrointestinal (GI) tract, and brain. You may also need blood transfusions. Fluid overload. However, each individual may experience symptoms differently. It’s done in an operating room under general anesthesia, which means you’re asleep and don’t feel anything. Although the new bone marrow may begin making cells in the first 30 days following transplant, it may take months, even years, for the entire immune system to fully recover. Bone marrow transplants may also be needed if the bone marrow has been destroyed by a disease. The day of transplant is numbered zero. Once the new cells reach your marrow, they’ll grow into red and white blood cells and platelets. Afterward, you’ll have large bandages over your hips that will need to stay on for 24 hours, and you can expect to be a little sore for a few days. Matching involves typing human leukocyte antigen (HLA) tissue. As with any procedure, in bone marrow transplant the prognosis and long-term survival can vary greatly from person to person. Acute leukemia 2. Choose foods that give your body the nutrients it needs. Whether they’re a relative or a stranger, the donor will go through the same process to collect their stem cells. Get your body ready to receive them (conditioning). Engraftment can be delayed because of infection, medicines, low donated stem cell count, or graft failure. Bone Marrow Transplant: Making the Decision. The mother decides ahead of time if they want to donate them, and the baby isn’t affected in any way.

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